The University of Arizona

Department of Physiology - The University of Arizona

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Faculty

Janis Burt

Professor

Contact Information

Address: P.O. Box 245051
Tucson, AZ 85724
Phone: (520) 626-6833
Email: jburt@email.arizona.edu


Website: http://www.physiology.arizona.edu/labs/burtlab/

Research Interests

Role of gap junctions in vascular function

Contribution of gap junctions to growth control, vascular remodeling, and response to injury and disease

Mechanisms underlying acute regulation of gap junction function by second messenger signaling cascades

Biophysics of gap junction channels

Gap Junctions in vascular smooth muscle: Growth control

Functional consequences of connexin interactions in blood vessels

Graduate Program Affiliations

Physiological Sciences

Publications

Heyman NS, Burt JM.. Feb 2008. Hindered diffusion through an aqueous pore describes invariant dye selectivity of. Biophysical Journal, 94:840-854 PMCID: 179

Lampe PD Cooper CD King TJ Burt JM. Aug 2006. Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart. J Cell Sci, 119:3435-42

Ek-Vitorin JF King TJ Heyman NS Lampe PD Burt JM. Jun 2006. Selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation. Circ Res, 98:1498-505

Ek-Vitorin JF, Burt JM. Aug 2005. Quantification of Gap Junction Selectivity. Am J Physiol Cell Physiol,2005 Aug 10;

Cottrell GT, Burt JM. Jun 2005. Functional consequences of heterogeneous gap junction channel formation and its influence in health and disease. Biochim Biophys Acta, 1711:126-41

Hirschi KK, Burt JM, Hirschi KD, Dai C. Sep 2003. Gap junction communication mediates transforming growth factor-beta activation and endothelial-induced mural cell differentiation. Circ Res, 93:429-37

Burt JM, Steele TD. Jul 2003. Selective effect of PDGF on connexin43 versus connexin40 comprised gap junction channels. Cell Commun Adhes, 10:287-91

Cottrell GT, Lin R, Warn-Cramer BJ, Lau AF, Burt JM. Feb 2003. Mechanism of v-Src- and mitogen-activated protein kinase-induced reduction of gap junction communication. Am J Physiol Cell Physiol, 284:C511-20

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