Chromatin interaction maps of human arterioles reveal mechanisms for the genetic regulation of blood pressure

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Fig. 5: BP-associated noncoding SNP rs1882961 interacts with NRIP1 promoter 119 kbp away and influences NRIP1 expression.

Fig. 5: BP-associated noncoding SNP rs1882961 interacts with NRIP1 promoter 119 kbp away and influences NRIP1 expression.

Y Liu, Pandey, Qiu, P Liu, Xue and colleagues report extensive maps of chromatin interactions, single-cell expression, and other molecular features in human arterioles and uncover mechanisms linking human genetic variants to gene expression in vascular cells and the development of hypertension.  

Read the full article on Nature.