Mingyu Liang, MB, PhD

Professor, Physiology
Department Head, Physiology
Research Interests

The Liang group studies molecular systems medicine. The current work in our group focuses on three areas: (epi)genomics and precision medicine, regulatory RNA, and cellular metabolism, as they relate to hypertension and cardiovascular and kidney diseases. We have a multidisciplinary, translational research platform where we integrate human research with animal, induced pluripotent stem cell (iPSC), and other model system research using approaches of physiology, multi-omics, single-cell and spatial omics, big data analysis, genome editing, genetics, biochemistry, and molecular and cell biology.


  • 1994 MB, Shanghai Medical University, Shanghai P.R. China
  • 1999 PhD Biomedical Sciences (Physiology), Mayo Graduate School
  • 2000 Research Fellow, Nephrology, Mayo Clinic and Foundation
  • 2002 Postdoctoral Fellow, Genomics, Medical College of Wisconsin
Publication Highlights

Kotchen TA, Cowley AW Jr, Liang M. Ushering hypertension into the new era of precisionmedicine. JAMA 2016; 315: 343-4

Williams AM, Jensen DM, Pan X, Liu P, Liu J, Huls S, Regner KR, Iczkowski KA, Wang F, Li J, GallanAJ, Wang T, Baker MA, Liu Y, Lalehzari N, Liang M. Histologically resolved small RNA maps inprimary focal segmental glomerulosclerosis indicate progressive changes within glomerular andtubulointerstitial regions. Kidney Int. 2022; 101(4):766-778

Widlansky ME, Liu Y, Tumusiime S, Hofeld B, Khan N, Aljadah M, Wang J, Anger A, Qiu Q, TheraniB, Liu P, Liang M. Coronary plaque sampling reveals molecular insights into coronary arterydisease. Circ Res 2023; 133(6):532-534